HTML5 Page Layout
The big change is that in HTML 5, you can use specific and meaningful containers instead of generic and meaningless div-tags. So instead of having a div for your header, a div for your menu and a div for your content, you can use the header, nav and article tags to really describe your web page.
Below is a really simple example of an HTML 5 page with semantic tags that help to describe the page.
This example was last updated on 16/08/2011 with changes to the use of the section element.